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Our Honeymoon May-June 2014 Part 5: Germany and UAE

Day 17- Warsaw, Poland to Berlin, Germany (6th June 2014) (continued from part 4) Following a delicious hotel buffet breakfast, we boarded the coach to begin our long…

Bardoxolone methyl prevents fat deposition and inflammation in the visceral fat of mice fed a high-fat diet

Key features of diet-induced obesity are visceral fat deposition, macrophage infiltration and inflammation that can lead to metabolic disorders. This study examined the effects of bardoxolone methyl (BARD)…

Bardoxolone methyl prevents high-fat diet-induced alterations in prefrontal cortex signalling molecules involved in recognition memory

High fat (HF) diets are known to induce changes in synaptic plasticity in the forebrain leading to learning and memory impairments. Previous studies of oleanolic acid derivatives have…

Is B-type Natriuretic Peptide a Risk Factor for Heart Failure in Patients Treated With Bardoxolone Methyl?

Camer D, Huang XF: Is B-type Natriuretic Peptide a Risk Factor for Heart Failure in Patients Treated With Bardoxolone Methyl? J Cardiac Fail 2015, 21: 258-259. (Letter to…

Our Honeymoon May-June 2014 Part 4: Belarus and Poland

Day 14- Moscow, Russia to Minsk, Belarus (3rd June 2014) (continued from part 3) After spending a number of magical days in Russia, it was time to hop…

The Endothelin Pathway: A Protective or Detrimental Target of Bardoxolone Methyl on Cardiac Function in Patients with Advanced Chronic Kidney Disease?

Bardoxolone methyl has been reported to cause detrimental cardiovascular events in the terminated BEACON Phase III human clinical trial via modulation of the renal endothelin pathway. However, the…

Our Honeymoon May-June 2014 Part 3: Novgorod and Moscow, Russia

Day 11- St Petersburg to Novgorod, Russia (31st May 2014) (continued from part 2) In the morning, it was time to leave the main centre of St Petersburg…

Oleanolic acid co-administration alleviates ethanol-induced hepatic injury via Nrf-2 and ethanol-metabolizing modulation (sic) in rats

Camer D, Huang XF: Comment on: Oleanolic acid co-administration alleviates ethanol-induced hepatic injury via Nrf-2 and ethanol-metabolizing modulation (sic) in rats. Chem Biol Interact 2014, 223C:116. (Letter to…

Our Honeymoon May-June 2014 Part 2: Finland and St Petersburg, Russia

Day 7- Stockholm, Sweden to Helsinki, Finland (27th May 2014) (continued from part 1) In the evening it was time to board our ship for an overnight trip…

Our Honeymoon May-June 2014 Part 1: Denmark and Sweden

Day 1- Copenhagen, Denmark (21st May 2014) After a 20+ hour flight, we arrived in Copenhagen, Denmark on a beautiful summer’s day. The hotel gave us a room…